In 1988, the KNCV Section Farmacochemie established a biannual award to be granted to the most outstanding doctoral dissertation in medicinal chemistry by a PhD student at a Dutch university. The first five prizes, the so-called MFR Medicinal Chemistry Prizes, were sponsored by MFR, a Dutch foundation aimed at promoting medicinal chemistry research. In 1998, sponsorship was taken over by Stichting Farmacochemische Congressen. In the period 2010-2017 the prize was sponsored by Mercachem, and since 2018 the prize is sponsored by MercachemSyncom. As of 2020, the Section Farmacochemie broadened her scope by changing her name to KNCV Medicinal Chemistry & Chemical Biology (MCCB). Accordingly, the biannual award is granted to the best doctoral dissertation in medicinal chemistry or chemical biology by a PhD student at a Dutch university.