Prelimenary programme
Theme: Medicinal Chemistry and Chemical Biology close to the Hospital
10:00 – 10:20 Registration & Coffee
10:20 – 10:30 Welcome – Ingrid Dijkgraaf (KNCV-MCCB)
Morning Session (Chair TBA)
10:30 – 11:10 Wilbert Zwart (Netherlands Cancer Institute)
Precision oncology in hormone-driven cancers; from trials to mechanisms and back again
11:10 – 11:30 Emira Visser (Eindhoven University of Technology)
Molecular glue for Metabolic control - Stabilizing the ChREBP/14-3-3 PPI
11:30 – 11:50 Coffee & Posters
11:50 – 12:20 Flash presentations
Carla Araya-Cloutier (WUR) Understanding the mode of action of antimicrobial prenylated isoflavonoids: an in-vitro and in-silico journey
Sean McKenna (Leiden Uni) COMBINAUT: Automated Parallel Synthesis Accelerates Virtual Screening Hit Discovery
12:20 – 13:00 Wouter Vaes (TNO)
Microtracers in clinical pharmacological research
13:00 – 14:00 Lunch / General Assembly / Posters
Afternoon Session (Chair TBA)
14:00 – 14:40 Rik van der Kant (Amsterdam UMC)
Discovering novel drugs for Alzheimer’s Disease using human brain cells.
14:40 – 15:10 Flash presentations (2 × 15 min)
Karlijn Meerman (RUG) Toward smart drugs using photoswitchable stapled peptides
Laura Wijffelaars (VU Amsterdam) The discovery of VUF26200: an azabicyclic ACKR3 inverse agonist
15:10 – 15:30 Coffee & Posters
15:30 – 15:45 Flash presentation (15 min)
Jana Volaric (Leiden University) Photocaging Enables Optical Control of S-acyltransferase Activity in Mammalian Cells
15:45 – 16:25 Daniëlle Vugts (VU Amsterdam Imaging Center)
Imaging during drug development
16:25 – 17:00 Networking Drinks
