Program Thursday March 30th 2023
| 09:15 | Welcome & Coffee |
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| 10:00 | Opening by Iwan de Esch and Kim Bonger | |
| Keynote I Chair: Tom Wennekes |
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| 10:05 | Hermen Overkleeft (LU) Exploring and exploiting glycosidase inhibitors in biomedicine and biotechnology |
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| Parallelsession I Chair: Eelco de Ruijter |
Parallelsession II Chair: Iwan de Esch |
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| 10:50 | Qiang Zheng (RUG) The isocyanide SN2 reaction |
Erianna Alvarado Melendeza (UU) Glycoengineering lipooligosaccharides on bacterial pathogens |
| 11:10 | Wouter Remmerswaal (LEI) Competing reactive intermediates in stereoselective glycosylation reactions |
Icaro Simon (VU) The PhotoSwitch Workflow: A computational workflow to design and virtually screen photoswitchable molecules |
| 11:30 | Michiel Uiterweerd (RUG) Total synthesis of lugdunomycin by a biomimetic reaction cascade |
Margot van Weijsten (RU) The effect of antigen valency on B-cell targeting in Rheumatoid Arthritis |
| 11:50 | Lunch & MCCB ALV (ALV starts at 12:30) | |
| Keynote II Chair: Kim Bonger |
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| 13:00 | Goncalo Bernardes (Cambridge University – Online Lecture) Translational Chemical Biology |
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| Parallelsession III Chair: Fedor Miloserdov |
Parallelsession IV Chair: Ingrid Dijkgraaf |
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| 13:45 | Mathilde Janssen (RU) Synthesis of Cyclobutanes for Fragment-Based Drug Discovery |
Albert Wong (TU) Brain-inspired Chemical Reaction Networks |
| 14:05 | Daan Bunt (RUG) Divergent Total Synthesis Of Meroterpenoids From Ganoderma Mushrooms |
Keiko Oike (TUD) Immobilisation of oleate hydratase on solid supports |
| 14:25 | Thomas Roose (VU) Iron-catalyzed carbene transfer to isocyanide |
Jun Yang Ong (UU) Chemoenzymatic Synthesis of 13C Enriched Sialic Acids |
| 14:45 | Coffee/Tea | |
| Keynote III & IV Chair: Bauke Albada |
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| 15:15 | Bart Herlé and Cedrickx Godboud (Boehringer Ingelheim) Discovery and Development of an ENaC Inhibitor for the Treatment of Cystic Fibrosis |
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| 15:45 | Laura Heitman (LU) Targeting chemokine receptor CCR2 - From insurmountable antagonists to affinity-based probes |
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| 16:30 | Posters & Drinks | |
| 18:00 | Dinner | |
Program Friday March 31th 2023
| Keynote V Chair Leendert van den Bos |
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| 09:00 | Floris van Delft (Synaffix) GlycoConnect™ immune cell engagers (GC™-ICEs). A non-genetic approach to targeted IL-15 immunotherapy |
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| Parallelsession V Chair: Mark Borst |
Parallelsession VI Chair: Leendert van den Bos |
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| 09:45 | Xin Li (RUG) Amenamevir by Ugi-4CR |
Lars Binkhorst (VU) VUF26026: a second-generation photoswitchable ligand for histamine H3 receptor photopharmacology |
| 10:05 | Brendan Horst (VU) Total Synthesis Of Complex Indole Alkaloids By A Nitroaryl Transfer Cascade Reaction |
Enebie Ramos Cáceres (RU) Lightening up NETosis |
| 10:25 | Benjamin Spitzbarth (TUD) Redox-controlled shunts in a synthetic chemical reaction cycle |
Chuanbao Zheng (WUR) Modular design for proteins assembling into antifouling coatings: case of gold surfaces |
| 10:45 | Coffee / Tea | |
| Keynote VI | ||
| 11:15 | Jurriaan Huskens (UT) Catching the Flu: A Supramolecular View on the Interaction of Viruses at Interfaces |
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| Parallelsession VII Chair: Pascal Jonkheijm |
Parallelsession VIII Chair: Bauke Albada |
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| 12:00 | Zonghao Lin (RUG) Asymmetric Total Synthesis and Structure Revision of Di-O-acyl Trehalose DAT2, an Antigenic Glycolipid from M. tuberculosis |
Max Kloet (LUMC) Activity-based profiling of legionella effectors |
| 12:20 | Jordy Saya (UM) Enhancing the speed of the Passerini reaction |
Lifeng Sun (UU) Well-defined Heparin Mimetics can Inhibit Binding of Trimeric Receptor Binding Domains of SARS-CoV-2 in a Length Dependent Manner |
| 12:40 | Lunch & SOC ALV (ALV starts at 13:15) | |
| Keynote VII - IX Chair: Tom Wennekes |
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| 13:50 | Announcement and Lecture winner The Backer-KNCV prize 2023 - Adri Minnaard | |
| 14:25 | Announcement and Lecture winner The MCCB thesis prize 2023 – Laura Heitman | |
| 15:00 | Ilja Voets (TuE) Ice-cold and crystal-clear: resolving the interfacial dynamics of individual ice-binders by nanoscopy to engineer novel cryoprotective compounds with modular activity |
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| 15:45 |
SOC & MCCB Prizes for best oral and poster presentations | |
| 15:55 | Closing followed by drinks | |
