Program Thursday March 30th 2023
Download the book of abstracts here
| 09:15 | Welcome & Coffee in FIRE |
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| 10:00 | Opening by Iwan de Esch, Tom Wennekes & Kim Bonger | |
| Keynote I in AIR | ||
| 10:05 | Hermen Overkleeft (LU) Exploring and exploiting glycosidase inhibitors in biomedicine and biotechnology |
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| Parallel session I in AIR Chair: Eelco Ruijter |
Parallel session II in WATER Chair: Iwan de Esch |
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| 10:50 | Jordy Saya (UM) Enhancing the speed of the Passerini reaction |
Erianna Alvarado Melendez (UU) Glycoengineering lipooligosaccharides on bacterial pathogens |
| 11:10 | Wouter Remmerswaal (LEI) Competing reactive intermediates in stereoselective glycosylation reactions |
Icaro Simon (VU) The PhotoSwitch Workflow: A computational workflow to design and virtually screen photoswitchable molecules |
| 11:30 | Michiel Uiterweerd (RUG) Total synthesis of lugdunomycin by a biomimetic reaction cascade |
Margot van Weijsten (RU) The effect of antigen valency on B-cell targeting in Rheumatoid Arthritis |
| 11:50 | Lunch in the Restaurant & MCCB ALV (ALV starts at 12:30 in AIR) | |
| Keynote II in AIR Chair: Kim Bonger |
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| 13:00 | Goncalo Bernardes (Cambridge University – Online Lecture) Translational Chemical Biology |
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| Parallel session III in AIR Chair: Fedor Miloserdov |
Parallel session IV in WATER Chair: Ingrid Dijkgraaf |
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| 13:45 | Mathilde Janssen (RU) Synthesis of Cyclobutanes for Fragment-Based Drug Discovery |
Albert Wong (TU) Brain-inspired Chemical Reaction Networks |
| 14:05 | Daan Bunt (RUG) Divergent Total Synthesis Of Meroterpenoids From Ganoderma Mushrooms |
Keiko Oike (TUD) Immobilisation of oleate hydratase on solid supports |
| 14:25 | Thomas Roose (VU) Iron-catalyzed carbene transfer to isocyanide |
Jun Yang Ong (UU) Chemoenzymatic Synthesis of 13C Enriched Sialic Acids |
| 14:45 | Coffee/Tea in FIRE | |
| Keynote III & IV in AIR Chair: Bauke Albada |
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| 15:15 | Bart Herlé and Cedrickx Godbout (Boehringer Ingelheim) Discovery and Development of an ENaC Inhibitor for the Treatment of Cystic Fibrosis |
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| 15:45 | Laura Heitman (LU) Targeting chemokine receptor CCR2 - From insurmountable antagonists to affinity-based probes |
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| 16:30 | Posters & Drinks in FIRE | |
| 18:00 | Dinner in the Restaurant | |
| 20:00 | Socializing & Borrel (in FIRE, bar open till midnight) | |
Program Friday March 31th 2023
| Keynote V in AIR Chair Leendert van den Bos |
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| 09:00 | Floris van Delft (Synaffix) GlycoConnect™ immune cell engagers (GC™-ICEs). A non-genetic approach to targeted IL-15 immunotherapy |
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| Parallel session V in AIR Chair: Mark Borst |
Parallel session VI in WATER Chair: Leendert van den Bos |
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| 09:45 | Xin Li (RUG) Amenamevir by Ugi-4CR |
Lars Binkhorst (VU) VUF26026: a second-generation photoswitchable ligand for histamine H3 receptor photopharmacology |
| 10:05 | Brendan Horst (VU) Total Synthesis Of Complex Indole Alkaloids By A Nitroaryl Transfer Cascade Reaction |
Enebie Ramos Cáceres (RU) Lightening up NETosis |
| 10:25 | Benjamin Spitzbarth (TUD) Redox-controlled shunts in a synthetic chemical reaction cycle |
Chuanbao Zheng (WUR) Modular design for proteins assembling into antifouling coatings: case of gold surfaces |
| 10:45 | Coffee / Tea in FIRE | |
| Keynote VI in AIR Chair: Pascal Jonkheijm |
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| 11:15 | Jurriaan Huskens (UT) Catching the Flu: A Supramolecular View on the Interaction of Viruses at Interfaces |
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| Parallel session VII in AIR Chair: Pascal Jonkheijm |
Parallel session VIII in WATER Chair: Bauke Albada |
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| 12:00 | Zonghao Lin (RUG) Asymmetric Total Synthesis and Structure Revision of Di-O-acyl Trehalose DAT2, an Antigenic Glycolipid from M. tuberculosis |
Max Kloet (LUMC) Activity-based profiling of legionella effectors |
| 12:20 | Qiang Zheng (RUG) The isocyanide SN2 reaction |
Lifeng Sun (UU) Well-defined Heparin Mimetics can Inhibit Binding of Trimeric Receptor Binding Domains of SARS-CoV-2 in a Length Dependent Manner |
| 12:40 | Lunch in the Restaurant & SOC ALV (ALV starts at 13:10 in AIR) | |
| Keynote VII - IX in AIR Chair: Tom Wennekes |
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| 13:50 | Announcement and Lecture winner The Backer-KNCV prize 2023 - Adri Minnaard | |
| 14:25 | Announcement and Lecture winner The MCCB thesis prize 2023 – Iwan de Esch | |
| 15:00 | Ilja Voets (TuE) Ice-cold and crystal-clear: resolving the interfacial dynamics of individual ice-binders by nanoscopy to engineer novel cryoprotective compounds with modular activity |
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| 15:45 |
SOC & MCCB Prizes for best oral and poster presentations | |
| 15:55 | Closing followed by drinks in FIRE | |
