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Program Lunteren 2023

Program Thursday March 30th 2023

09:15 Welcome & Coffee
10:00 Opening by Iwan de Esch and Kim Bonger
Keynote I
Chair: Tom Wennekes
10:05 Hermen Overkleeft (LU)
Exploring and exploiting glycosidase inhibitors in biomedicine and biotechnology
Parallelsession I
Chair: Eelco de Ruijter
Parallelsession II
Chair: Iwan de Esch
10:50 Qiang Zheng (RUG)
The isocyanide SN2 reaction
Erianna Alvarado Melendeza (UU)
Glycoengineering lipooligosaccharides on bacterial pathogens
11:10 Wouter Remmerswaal (LEI)
Competing reactive intermediates in stereoselective glycosylation reactions
Icaro Simon (VU)
The PhotoSwitch Workflow: A computational workflow to design and virtually screen photoswitchable molecules
11:30 Michiel Uiterweerd (RUG)
Total synthesis of lugdunomycin by a biomimetic reaction cascade
Margot van Weijsten (RU)
The effect of antigen valency on B-cell targeting in Rheumatoid Arthritis
11:50 Lunch & MCCB ALV (ALV starts at 12:30)
  Keynote II
Chair: Kim Bonger
13:00 Goncalo Bernardes (Cambridge University – Online Lecture)
Translational Chemical Biology
Parallelsession III
Chair: Fedor Miloserdov
Parallelsession IV
Chair: Ingrid Dijkgraaf
13:45 Mathilde Janssen (RU)
Synthesis of Cyclobutanes for Fragment-Based Drug Discovery
Albert Wong (TU)
Brain-inspired Chemical Reaction Networks
14:05 Daan Bunt (RUG)
Divergent Total Synthesis Of Meroterpenoids From Ganoderma Mushrooms
Keiko Oike (TUD)
Immobilisation of oleate hydratase on solid supports
14:25 Thomas Roose (VU)
Iron-catalyzed carbene transfer to isocyanide
Jun Yang Ong (UU)
Chemoenzymatic Synthesis of 13C Enriched Sialic Acids
14:45 Coffee/Tea
  Keynote III & IV
Chair: Bauke Albada
15:15 Bart Herlé and Cedrickx Godboud (Boehringer Ingelheim)
Discovery and Development of an ENaC Inhibitor for the Treatment of Cystic Fibrosis
15:45 Laura Heitman (LU)
Targeting chemokine receptor CCR2 - From insurmountable antagonists to affinity-based probes
16:30 Posters & Drinks
18:00 Dinner

 

Program Friday March 31th 2023

Keynote V
Chair Leendert van den Bos
09:00 Floris van Delft (Synaffix)
GlycoConnect™ immune cell engagers (GC™-ICEs). A non-genetic approach to targeted IL-15 immunotherapy
Parallelsession V
Chair: Mark Borst
Parallelsession VI
Chair: Leendert van den Bos
09:45 Xin Li (RUG)
Amenamevir by Ugi-4CR
Lars Binkhorst (VU)
VUF26026: a second-generation photoswitchable ligand for histamine H3 receptor photopharmacology
10:05 Brendan Horst (VU)
Total Synthesis Of Complex Indole Alkaloids By A Nitroaryl Transfer Cascade Reaction
Enebie Ramos Cáceres (RU)
Lightening up NETosis
10:25 Benjamin Spitzbarth (TUD)
Redox-controlled shunts in a synthetic chemical reaction cycle
Chuanbao Zheng (WUR)
Modular design for proteins assembling into antifouling coatings: case of gold surfaces
10:45 Coffee / Tea
  Keynote VI
11:15 Jurriaan Huskens (UT)
Catching the Flu: A Supramolecular View on the Interaction of Viruses at Interfaces
Parallelsession VII
Chair: Pascal Jonkheijm
Parallelsession VIII
Chair: Bauke Albada
12:00 Zonghao Lin (RUG)
Asymmetric Total Synthesis and Structure Revision of Di-O-acyl Trehalose DAT2, an Antigenic Glycolipid from M. tuberculosis
Max Kloet (LUMC)
Activity-based profiling of legionella effectors
12:20 Jordy Saya (UM)
Enhancing the speed of the Passerini reaction
Lifeng Sun (UU)
Well-defined Heparin Mimetics can Inhibit Binding of Trimeric Receptor Binding Domains of SARS-CoV-2 in a Length Dependent Manner
12:40 Lunch  & SOC ALV (ALV starts at 13:15)
  Keynote VII - IX
Chair: Tom Wennekes
13:50 Announcement and Lecture winner The Backer-KNCV prize 2023 - Adri Minnaard
14:25 Announcement and Lecture winner The MCCB thesis prize 2023 – Laura Heitman
15:00 Ilja Voets (TuE)
Ice-cold and crystal-clear: resolving the interfacial dynamics of individual ice-binders by nanoscopy to engineer novel cryoprotective compounds with modular activity
15:45
SOC & MCCB Prizes for best oral and poster presentations
15:55 Closing followed by drinks

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